Chemical characterization of milk oligosaccharides of a spotted hyena (Crocuta crocuta)

The Carnivora include the superfamilies Canoidea and Feloidea. In species of Canoidea other than Canidae, the milk contains only traces of lactose and much larger concentrations of oligosaccharides. In this study, the following oligosaccharides were characterized in the milk of a spotted hyena, which is a species of Feloidea species: Neu5Ac(α2-3)Gal(β1-4)Glc, Gal(α1-3)[Fuc(α1-2)]Gal(β1-4)Glc, Gal(α1-3)Gal(β1-4)Glc and Fuc(α1-2)Gal(β1-4)Glc. Lactose was found to be the predominant saccharide; in this respect, the hyena milk is markedly different from the milks of most species of Canoidea species. The sole presence of 3′-SL in the spotted hyena milk is interesting, because the co-presence of 3′-SL and 6′-SL has been reported in the milk or colostrum of many mammalian species.