Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1982252 | Insect Biochemistry and Molecular Biology | 2012 | 8 Pages |
Abstract
⺠PTTH rapidly enhanced the phosphorylation of 4E-BP and S6K of prothoracic glands in Bombyx mori. ⺠Rapamycin treatment attenuated PTTH-stimulated phosphorylation of 4E-BP and S6K. ⺠PTTH-stimulated ecdysteroidogenesis was also inhibited by rapamycin treatment. ⺠PTTH/PI3K/TOR/4E-BP (S6K) signaling appears to be involved in PTTH-stimulated ecdysteroidogenesis.
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Authors
Shi-Hong Gu, Wei-Lan Yeh, Shun-Chieh Young, Pei-Ling Lin, Sheng Li,