Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1982267 | Insect Biochemistry and Molecular Biology | 2012 | 12 Pages |
Abstract
⺠Isopentenyl diphosphate isomerase of the spruce budworm (C. fumiferana) and the tobacco hornworm (M. sexta) was cloned. ⺠C. fumiferana isopentenyl diphosphate isomerase (IPPI) was expressed and characterized. ⺠A homology model of C. fumiferana was developed. ⺠Mutagenesis and inhibitor studies were performed to establish structural differences between lepidopteran and other IPPIs. ⺠The regiospecificity of homologous IPP isomerization by C. fumiferana IPPI was assessed.
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Authors
Stephanie E. Sen, Ashley Tomasello, Michael Grasso, Ryan Denton, Joseph Macor, Catherine Béliveau, Michel Cusson, Dring N. Crowell,