| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1982281 | Insect Biochemistry and Molecular Biology | 2012 | 12 Pages |
Abstract
⺠Drosophila NPC2 proteins can be divided into three subgroups based on the numbers of cysteine residues. ⺠NPC2a, NPC2e and NPC2h, representing the three subgroups, are selected for further study. ⺠The three NPC2 proteins can bind to lipopolysaccharide, lipid A, peptidoglycan and lipoteichoic acid. ⺠Over-expression of NPC2a and NPC2e can stimulate diptericin promoter in S2 cells induced by peptidoglycan. ⺠NPC2 proteins may serve as co-receptors for different ligands to modulate immune signaling pathways.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Insect Science
Authors
Xiu-Zhen Shi, Xue Zhong, Xiao-Qiang Yu,