Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2045251 | Current Biology | 2007 | 4 Pages |
Abstract
Polo-like kinase 1 (Plk1) regulates mitotic progression in all eukaryotes and has been implicated in the transformation of human cells. Analysis of the cytological and anti-tumor activities of BI 2536, a novel, selective pharmacological inhibitor of Plk1, has connected chemistry and biology to the bedside.
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Authors
Simon Plyte, Andrea Musacchio,