Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2046865 | Current Opinion in Plant Biology | 2011 | 6 Pages |
Processing bodies (P-bodies) contain RNA–protein complexes linked to cytoplasmic RNA decay pathways including mRNA decapping, nonsense-mediated decay (NMD) and small RNA-mediated decay. Plants deficient in P-body components display severe developmental perturbations, suggesting that these cytoplasmic bodies play important roles in regulating gene expression during plant development. Here, we summarize recent progress in the genetic dissection of P-body components and their roles in translational repression and mRNA decapping.
Research highlights▶ Developmental defects in mutants of P-body components are pleiotropic. ▶ P-body components are required for developmental transition or reprogramming. ▶ A kinetic model of translational repression and decapping in P-bodies.