Article ID Journal Published Year Pages File Type
2047887 FEBS Letters 2012 6 Pages PDF
Abstract

Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in d-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the d-galactose oxido-reductive pathway, but not the Leloir pathway in A. niger.

► Aspergillus niger only contains one of the two galactose regulators previously identified in Aspergillus nidulans. ► A. niger GalX does not regulate the Leloir pathway. ► A. niger GalX controls the d-galactose catabolic oxido-reductive pathway.

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