| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2047975 | FEBS Letters | 2012 | 9 Pages |
Abstract
SMAD transcription factors are key mediators of the transforming growth factor-beta (TGFß) family of cytokines. Reversible phosphorylation of SMAD proteins plays a key role in regulating their function. Several phosphatases have been proposed to act on SMAD proteins to influence TGFß/BMP signalling. Here we provide an overview of the SMAD regulation by different protein phosphatases and review the evidence supporting each phosphatase as a candidate SMAD-phosphatase.
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Authors
David L. Bruce, Gopal P. Sapkota,