| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2048730 | FEBS Letters | 2010 | 5 Pages |
Abstract
Pseudomonas aeruginosa secretes the fluorescent siderophore, pyoverdine (PVD), to enable iron acquisition. Epifluorescence microscopy and cellular fractionation were used to investigate the role of an efflux pump, PvdRT-OpmQ, in PVD secretion. Bacteria lacking this efflux pump accumulated PVD, or a fluorescent precursor, in the periplasm, due to their inability to efficiently secrete into the media newly synthesized PVD. PvdRT-OpmQ is only the second system identified for secretion of newly synthesized siderophores by Gram negative bacteria.
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Authors
Mélissa Hannauer, Emilie Yeterian, Lois W. Martin, Iain L. Lamont, Isabelle J. Schalk,