Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2049239 | FEBS Letters | 2010 | 7 Pages |
Abstract
Autophagy is a system for degradation of bulk cellular components in lytic compartments, vacuoles, or lysosomes when eukaryotic cells face with nutrient starvation. In this review, we focus on the pre-autophagosomal structure (PAS), a functional entity responsible for autophagosome formation in Saccharomyces cerevisiae, and discuss its relevance to autophagy in mammalian cells.
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Authors
Kuninori Suzuki, Yoshinori Ohsumi,