Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2049241 | FEBS Letters | 2010 | 6 Pages |
Abstract
Autophagosomes (APs) are unique organelles that enwrap cytoplasmic components when necessary. APs then fuse with lysosomes and enclosed materials are degraded. Although approximately 30 autophagy-related genes (ATG) required for AP formation have been identified, fundamental questions on the membrane source or dynamics during the formation remain unresolved. Here, we present a comprehensive overview of the putative membrane sources identified to date.
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Authors
Maho Hamasaki, Tamotsu Yoshimori,