| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2049572 | FEBS Letters | 2007 | 4 Pages |
Abstract
It is known that c-kit+ cells are increased in heart after infarction. The exact origins of the cardiac c-kit+ cells remain to be determined. We asked whether adipose tissue could be a potential source of c-kit+ cells. Our data show that the number of c-kit+ cells increased in adipose tissue derived stem cells when cultured with conditioned medium from neonatal cardiomyocytes grown under serum deprivation and hypoxia condition. We also found that VEGF receptor Flk-1 is involved in c-kit up regulation via ERK-mediated pathway.
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Authors
Xiaowen Bai, Sanga Sadat, Sebastian Gehmert, Eckhard Alt, Yao-Hua Song,