Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2049777 | FEBS Letters | 2009 | 6 Pages |
Abstract
Yeast cell cycle Boolean network was used as a case study of robustness to protein noise. Robustness was interpreted as involving stability of G1 steady state and sequence of gene expression from cell cycle START to stationary G1. A robustness measure to evaluate robustness strength of a network was proposed. Robust putative networks corresponding to the same steady state and sequence of gene expression of wild-type network were sampled. Architecture of wild-type yeast cell cycle network can be revealed by average topology profile of sampled robust putative networks.
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Authors
Wen-Bin Lee, Jiun-Yan Huang,