| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2050445 | FEBS Letters | 2008 | 6 Pages |
Cellular cAMP level increased dramatically upon rehydration following dehydration for 24 h in Anabaena sp. PCC 7120, but not in disruptant of an adenylate cyclase gene, cyaC. Oxygen consumption in the cyaC disruptant upon rehydration was higher than that in wild-type strain. Determination of lipid peroxidation and protein carbonylation of the cells revealed greater oxidative stress in the cyaC disruptant than in the wild-type strain during rehydration. Addition of cAMP or KCN to the cyaC disruptant decreased cellular oxygen consumption upon rehydration and oxidative damage. These results suggest that respiration upon rehydration is regulated by cAMP and that the higher respiration activity results in more oxidative damage in cyaC disruptant.
