Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2052800 | FEBS Letters | 2005 | 6 Pages |
Abstract
The exact phenotype and lineage of endothelial progenitor cells (EPCs) are still a matter of debate and different expansion protocols are used to obtain them. In this study, EPC expansion from peripheral blood mononuclear cells was analyzed within the first week of culture. Both the adherent and suspended cells, of which the latter usually discarded, were considered. We provide, for the first time, a systematic study of EPC phenotype and functional features within the first 3 days of culture. Moreover, within the 2nd day, both cellular fractions displayed a significant increase in endothelial marker expression which correlated with EPC properties.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Plant Science
Authors
Lydia Bellik, Fabrizio Ledda, Astrid Parenti,