Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2053403 | FEBS Letters | 2005 | 5 Pages |
Abstract
Expression of several virulence factors in the plant pathogen bacterium Ralstonia solanacearum is controlled by a complex regulatory network, at the center of which is PhcA. We provide genetic evidence that PhcA also represses the expression of hrp genes that code for the Type III protein secretion system, a major pathogenicity determinant in this bacterium. The repression of hrp genes in complete medium is relieved in a phcA mutant and two distinct signals, a quorum-sensing signal and complex nitrogen sources, appear to trigger this PhcA-dependent repression. This control of hrp gene expression by PhcA is realized at the level of the HrpG regulatory protein.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Plant Science
Authors
Stéphane Genin, Belen Brito, Timothy P. Denny, Christian Boucher,