| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2054714 | International Journal for Parasitology: Drugs and Drug Resistance | 2012 | 4 Pages |
Dientamoeba fragilis is a debated protozoan parasite that is often detected in stools of patients with chronic gastro-intestinal complaints. A retrospective follow-up study of a large cohort of patients was performed to better understand the natural course of the infection and possible treatment options. D. fragilis was spontaneously cleared in 41% of untreated cases. With an eradication rate of 98%, treatment with paromomycin appeared more effective than treatment with clioquinol (83%) or metronidazole (57%).
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights• Study on efficacy of drugs and natural course to eradicate Dientamoeba fragilis. • Paromomycin treatment eradicated Dientamoeba fragilis in 60/61 patients (98%). • D. fragilis infections were spontaneously cleared in 9/22 untreated patients (41%).
