Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2075298 | Biocatalysis and Agricultural Biotechnology | 2015 | 7 Pages |
Abstract
This paper describes the search for novel vegetal biocatalysts for the stereoselective reduction of prochiral phenylketones. In this study, twenty native weeds were tested and Eryngium horridum Malme (Apiaceae) was proven to be an effective biocatalyst for the stereoselective reduction of acetophenone to (S)-1-phenylethanol (96% conversion, >99.9 e.e.%). Using this biocatalyst, fourteen chiral (S)-phenylethanols with excellent enantiomeric excesses (>98%) and variable conversions (30-100%) were obtained.
Keywords
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Agricultural and Biological Sciences
Agricultural and Biological Sciences (General)
Authors
Daniela L. Bordón, Leonardo D. Villalba, Mario L. Aimar, Juan J. Cantero, Ana M. Vázquez, Stella M. Formica, Claudio R. Krapacher, Laura I. Rossi,