Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2075684 | Biocatalysis and Agricultural Biotechnology | 2013 | 4 Pages |
Abstract
Sulfide oxidase activity of Streptomyces genus is reported here for the first time. Three Streptomyces strains were selected as new tools to access to enantioenriched R- and S-dialkyl sulfoxides. The bacterial screening was carried out using cyclohexyl methyl sulfide as model substrate. Both sulfoxide antipodes were obtained in a one-pot, time-dependent biotransformation employing Streptomyces phaeochromogenes NCIMB 11741 as biocatalyst. Streptomyces flavogriseus ATCC 33331produced mainly the S-enantiomer, while Streptomyces hiroshimensis ATCC 27429 yielded enantiopure R-cyclohexyl methyl sulfoxide.
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Authors
Maria Laura Mascotti, Martin Alejandro Palazzolo, Elizabeth Lewkowicz, Marcela Kurina-Sanz,