| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2093919 | Stem Cell Research | 2015 | 4 Pages |
Abstract
An induced pluripotent stem cell line was generated from primary human bone marrow derived mesenchymal stromal cells of a 74 year old donor using retroviruses harboring OCT4, SOX2, KLF4 and c-MYC in combination with the following inhibitors TGFβ receptor-SB 431542, MEK-PD325901, and p53-Pifithrin α. Pluripotency was confirmed both in vitro and in vivo.
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Authors
Matthias Megges, Sven Geissler, Georg N. Duda, James Adjaye,