Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2093923 | Stem Cell Research | 2015 | 4 Pages |
Abstract
Human dermal fibroblasts from a Nijmegen Breakage Syndrome (NBS) patient bearing the 657del5 mutation within the DNA repair gene NIBRIN were used to generate two iPSC-lines (vNBS8-iPS-c1, vNBS8-iPS-c2) by retroviral transduction of OCT4, SOX2, c-MYC and KLF4. Pluripotency was confirmed both in vivo and in vitro.
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Authors
Barbara Mlody, James Adjaye,