Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2094125 | Stem Cell Research | 2016 | 5 Pages |
Abstract
Skin biopsies were collected from three male patients (age 45, 44 and 44) with clinically diagnosed schizophrenia. The patients were diagnosed according to DSM-5 criteria by a trained psychiatrist. Dermal fibroblast cell lines were established and expanded for subsequent reprogramming procedures. Induced pluripotent stem (iPS) cells were derived using the integration-free CytoTune®-iPS 2.0 Sendai Reprogramming Kit, containing Sendai virus particles of the four Yamanaka factors Oct3/4, Sox2, Klf4 and c-Myc.
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Authors
Jaroslaw Sochacki, Sylvie Devalle, Marcelo Reis, Renata de Moraes Maciel, Bruna da Silveira Paulsen, Helena Brentani, Paulo Silva Belmonte-de-Abreu, Stevens Rehen,