| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2169191 | Cryobiology | 2009 | 6 Pages |
Abstract
The carbohydrates sucrose, trehalose and raffinose were tested in different concentrations or mixtures in order to increase the product stability of the S9-fraction during and after freeze-drying. The activity of the freeze-dried S9-samples was evaluated by means of their potential to activate pre-genotoxic compounds. The successful long-term stabilization of enzymes of the rodent liver S9-fraction for 6 weeks at room temperature by freeze-drying in the presence of 250Â mM trehalose is presented.
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Authors
Sebastian Buchinger, Elisabeth Campen, Eckard Helmers, Valeri Morosow, Marianne Krefft, Georg Reifferscheid,