Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2178625 | European Journal of Cell Biology | 2011 | 8 Pages |
Abstract
This article addresses the multiple activities of actin. Starting out with the history of actin's discovery, purification and structure, it emphasizes the close relation between structure and function. In this context, we also point to unconventional actin conformations. Their existence in living cells is not yet well documented, however, they seem to play a special role in the supramolecular patterning that underlies some of the physiological functions of actin. Conceivably, such conformations may contribute to actin's diverse activities in the nucleus that are poorly understood so far.
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Authors
Cora-Ann Schoenenberger, Hans Georg Mannherz, Brigitte M. Jockusch,