Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2180527 | Fungal Biology Reviews | 2012 | 12 Pages |
Abstract
⺠C. neoformans causes life-threatening meningoencephalitis in people with HIV/AIDS. ⺠Dissemination of the fungus from the lung to the brain is poorly understood. ⺠A variety of diverse functions influence virulence and the dissemination process. ⺠Animal models and in vitro assays are critical for evaluating dissemination factors. ⺠Cell wall melanin and specific enzymes are key factors in egress from the lung.
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Authors
E.J. Griffiths, M. Kretschmer, J.W. Kronstad,