Article ID Journal Published Year Pages File Type
2180527 Fungal Biology Reviews 2012 12 Pages PDF
Abstract
► C. neoformans causes life-threatening meningoencephalitis in people with HIV/AIDS. ► Dissemination of the fungus from the lung to the brain is poorly understood. ► A variety of diverse functions influence virulence and the dissemination process. ► Animal models and in vitro assays are critical for evaluating dissemination factors. ► Cell wall melanin and specific enzymes are key factors in egress from the lung.
Related Topics
Life Sciences Agricultural and Biological Sciences Agricultural and Biological Sciences (General)
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