Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2397707 | Journal of Feline Medicine & Surgery | 2011 | 5 Pages |
Abstract
This paper documents the first reported case of fucosidosis in a cat. The cat presented with signs of forebrain and cerebellar dysfunction and a magnetic resonance imaging scan of the brain suggested a degenerative or metabolic disease process. A fine needle aspirate of grossly normal lymph nodes revealed vacuolated lymphocytes and a renal biopsy of an irregular shaped kidney identified vacuolated tubular epithelial cells. A white cell lysosomal enzyme screen revealed negligible α-fucosidase activity. Fucosidosis should be considered in the differential diagnosis of young cats with cerebellar dysfunction and must be added to the list of lysosomal storage diseases affecting the cat.
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Authors
Lorna P. MA, VetMB, MRCVS, Annette M. MVB, CertSAM, CertVDI, MRCVS, Yoshika PhD, DVM, Peter M. BVM&S, BSc, PhD, DipECVN, MRCVS,