Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2397809 | Journal of Feline Medicine & Surgery | 2011 | 5 Pages |
Abstract
A new fipronil-based spot-on formulation was evaluated against experimental flea infestations in cats in two studies. In both studies, eight cats served as negative controls (groups 1 and 4); on day 0, eight cats were treated with a 10% w/v fipronil-based spot-on solution (Effipro Spot-on, 0.5Â ml per cat, groups 2 and 5) and eight cats served as positive controls (Frontline Spot-on, 0.5Â ml per cat, groups 3 and 6). Each cat was infested on day - 1 with 50 fleas (study 1) and weekly (day 7-day 56) with 100 fleas (study 2). Geometric mean flea counts obtained 48Â h after the treatment or each re-infestation were reduced by 99.0 and 98.3% in groups 2 and 3, respectively, on day 2, compared to the negative control group. Cats were protected from re-infestations with an efficacy >99% for 58 days in group 5 and for 37 days in group 6.
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Authors
Marie-Christine DrMedvet, DipECVD, PhD, MRCVS, Stéphane G. MD Parasitology, Josephus J. MSc,