Idiopathic inflammatory bowel disease in cats: Rational treatment selection

Practical relevanceInflammatory bowel disease (IBD) is a common diagnosis in cats with chronic gastrointestinal signs. Its management presents clinical challenges, not least because rational therapy relies on a definitive diagnosis, and current understanding of the underlying pathogenesis has, to date, limited the development of specific therapies. The mainstays of treatment remain dietary manipulation and immunosuppressive theraphy, but treatment failures are not uncommon. A logical clinical approach is important and there are a number of alternative or adjunctive treatments that can prove useful in refractory cases.Evidence baseThis article draws on data from clinical trials in humans, in vitro studies, prospective and retrospective studies in cats with naturally occurring IBD, and clinical experience to discuss the work-up and treatment selection for cats with idiopathic IBD.Patient groupIBD affects young adult to geriatric cats of both sexes.AudienceCompanion animal and feline practitioners are at the front line when it comes to managing these often challenging cases.