Subcutaneous phaeohyphomycosis due to Phialemoniopsis ocularis successfully treated by voriconazole

•Subcutaneous phaeohyphomycosis was histopathologically proven in a Cambodian patient.•The species Phialemoniopsis ocularis was identified by phenotypic and molecular techniques.•The clinical outcome was satisfactory after a 6-month treatment with oral voriconazole alone.

We report a case of subcutaneous infection in a 67 year-old Cambodian man who presented with a 5-month history of swelling of the right foot. Histopathology was compatible with phaeohyphomycosis and the hyphomycete Phialemoniopsis ocularis was identified by the means of morphological and molecular techniques. The patient responded well to a 6-month oral treatment with voriconazole alone.