Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2401262 | Topics in Companion Animal Medicine | 2012 | 7 Pages |
Abstract
Blood coagulation is a complex and highly coordinated process that is constantly altered and impacted by procoagulant and anticoagulant “players.” It is vital that these components work in concert to maintain a balance to keep coagulation in check. Several important endogenous anticoagulants will be discussed in this review including tissue factor pathway inhibitor, antithrombin, protein C, and protein S in origin, structure, mechanism of action, effects of deficiency, and current knowledge in veterinary medicine.
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Authors
Amy Kubier, Mauria O'Brien,