| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2426056 | Aquaculture | 2006 | 21 Pages |
One of the most important problems in fish husbandry is effective control of infectious diseases. In that respect one of several strategies is the use of antibacterial agents. Due to their low minimum inhibitory concentration (MIC) value for most susceptible fish pathogens and effective systemic distribution, quinolones is an important group of antibacterial agents used to treat bacterial diseases in fish.It is important that therapeutic regimes are designed to maximise efficacy and thereby minimise the risk of the development of resistant pathogens. In that respect, the study of the pharmacokinetic properties of drugs, in combination with susceptibility test, is an important tool for the establishment of optimal dosage regimes and thus the promotion of their correct use. This review summarises the state of knowledge of the pharmacokinetic properties of the most employed quinolones in fish. Fresh- and seawater, and cold- and warm water species are included in the review.
