| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2428530 | Comparative Immunology, Microbiology and Infectious Diseases | 2010 | 5 Pages |
Abstract
In order to demonstrate the potential to distinguish paratuberculosis (PTB) from bovine tuberculosis infection (TB), ELISAs with M. bovis-specific MPB70 or MPB83 as capture antigens were developed and tested on two groups of cattle: Group A comprised 23 animals positive for Mycobacterium avium paratuberculosis (Map) and TB free. Group B comprised 48 animals from a Map free herd during the previous 5 years, but confirmed as tuberculous by positive results on PPD testing and M. bovis culture. Results demonstrated a significant difference (p < 0.01) between reactivity of sera from these groups, encouraging the study of purified proteins to differentiate between both diseases.
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Authors
Carla D. Marassi, Jim McNair, John Pollock, Paula Ristow, Leila S. Fonseca, Walter M.R. Oelemann, Walter Lilenbaum,