Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2438324 | Journal of Comparative Pathology | 2010 | 4 Pages |
Abstract
SummaryAn adult horse was presented with a mass located within the dermis and subcutis of the right forelimb. At post-mortem examination there was a marked increase in thickness of the subcutis of the right forelimb extending from the fetlock to the pectoral muscles. Microscopically, the dermis and subcutis were diffusely infiltrated by endothelial-like cells forming irregular channels and cavernous spaces. Immunohistochemical examination revealed the endothelial-like cells to express vimentin, factor VIII-related antigen and PROX-1, confirming the identity of the tumour as a lymphangioma. Ultrastructural analysis showed that the cavernous spaces were lined by a discontinuous endothelium lacking any basement membrane.
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Authors
J. Junginger, A. Rötting, C. Staszyk, K. Kramer, M. Hewicker-Trautwein,