Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2438544 | Journal of Comparative Pathology | 2008 | 5 Pages |
Abstract
SummaryTissues from nine ferrets with granulomatous lesions similar to those seen in feline infectious peritonitis were examined histopathologically and immunohistochemically. Four main types of lesions were observed: diffuse granulomatous inflammation on serosal surfaces; granulomas with areas of necrosis; granulomas without necrosis; and granulomas with neutrophils. Other less commonly seen lesions were granulomatous necrotizing vasculitis and endogenous lipid pneumonia. FCV3-70 monoclonal antibody produced immunolabelling of group 1 coronavirus antigen in tissue samples from eight animals, the antigen being present in the cytoplasm of macrophages in the different types of granulomatous lesions.
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Authors
J. Martínez, M. Reinacher, D. Perpiñán, A. Ramis,