| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2438609 | Journal of Comparative Pathology | 2006 | 6 Pages |
Abstract
SummaryPleomorphic adenomas of the salivary gland were diagnosed in two dogs. The tumours were single, firm and well circumscribed, with a smooth cut surface. Metastatic tumours were not detected. Histopathological examination revealed that the tumours contained multiple cysts lined with luminal epithelial cells and myoepithelial cells, and mucinous, myxochondroid and cartilaginous tissues. Immunohistochemical examination demonstrated labelling of luminal epithelial cells and myoepithelial cells, and mucinous, myxochondroid and cartilaginous tissues with antibodies to cytokeratin LU-5, AE1/AE3, CK-14, CALP, a-SMA, vimentin, GFAP, and S-100. Labelling for GFAP indicated stromal transformation into myxoid and chondroid tissues.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Animal Science and Zoology
Authors
Y. Shimoyama, K. Yamashita, T. Ohmachi, Y. Akihara, T. Sako, K. Hirayama, M. Okamoto, H. Taniyama,