Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2452806 | Preventive Veterinary Medicine | 2011 | 7 Pages |
Abstract
The cELISA titers of goats from Mmc-infected and non-infected herds were comparable and negative using the accepted cutoff for bovine sera. In contrast, seroconversion was observed in goats experimentally inoculated with an Mmc strain that cross-reacted with a monoclonal antibody targeting the same epitope as that used in cELISA. The probability of such false positivity occurring under field conditions is very low since Mmc strains with such an atypical antigenic profile emerge only rarely as a result of random nucleotide variation of the epitope-coding region. In conclusion, the commercially available cELISA can be considered specific enough to be used as a primary test to monitor passage of the CBPP agent in goats, but its sensitivity in goats requires further investigation.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Animal Science and Zoology
Authors
Florence Tardy, Patrice Gaurivaud, LucÃa Manso-Silván, François Thiaucourt, Marie-Pierre Pellet, Pascale Mercier, Dominique Le Grand, François Poumarat,