Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2455465 | Research in Veterinary Science | 2012 | 4 Pages |
Abstract
Equine herpesvirus type 1 (EHV-1) is associated with abortions, respiratory distress, and neurological disturbances in horses. The ORF37 of EHV-1 encodes a protein homolog to UL24 gene product of human herpesvirus that has been associated with neurovirulence. In the present work, ORF37 PCR fragments derived from two Brazilian EHV-1 isolates, a German isolate and an American reference strain were sequenced and characterized by molecular phylogenetic analysis. This genomic region is highly conserved an allowed to infer genetic distances between EHV-1 strains and other animal herpesvirus.
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Authors
R.F. Carvalho, F.R. Spilki, E.M. Cunha, R.C. Stocco, C.W. Arns,