| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2455866 | Research in Veterinary Science | 2011 | 4 Pages |
Post mortem liver samples from 12 donkeys (Equus asinus) aged 21–57 years (4 females, 1 stallion, 7 geldings), were assessed chemically for copper and iron content on a wet weight basis and histologically for stainable iron. Chemical liver copper content ranged from 2.7 to 4.8 μg/g (mean 3.5 ± 0.05 μg/g). Chemical liver iron content ranged from 524 to 5010 μg/g (mean 1723 ± 1258 μg/g). Histochemical iron was measured morphometrically using a computer-based image analysis system; percentage section area staining for iron ranged from 0.84% to 26.69% (mean 10.82 ± 8.36%). There was no clear correlation, within the wide range of iron values, between histochemically demonstrable iron and chemically measured iron content. No clear age-related increase was apparent for either parameter in these aged donkeys. The accumulation of iron in the liver of donkeys may represent a physiological haemosiderosis rather than pathological haemochromatosis.
