Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2461814 | Veterinary Immunology and Immunopathology | 2012 | 4 Pages |
Abstract
The present study investigated IgE reactivity to a new Cryptomeria japonica pollen allergen (Cry j 3) in dogs with atopic dermatitis by using a fluorometric ELISA. Serum samples from 15 dogs that showed IgE sensitivity to crude C. japonica pollen allergen by ELISA were tested for specific IgE to each allergen, individually. All 15 dogs had anti-Cry j 1 IgE, 6 (40%) had anti-Cry j 2 IgE, and 11 (73%) had anti-Cry j 3 IgE. Further, we found that these anti-Cry j 3 IgE reacted to Cry j 3 with immunoblotting analysis. These findings indicate that Cry j 3 may be a major allergen in dogs.
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Authors
Shota Kubota, Kazuki Miyaji, Yusaku Shimo, Hidekatsu Shimakura, Yukari Takase, Noriaki Okamoto, Akio Kiuchi, Masato Fujimura, Takashi Fujimura, Douglas J. DeBoer, Toshihiro Tsukui, Masahiro Sakaguchi,