| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2462091 | Veterinary Immunology and Immunopathology | 2011 | 9 Pages |
Abstract
This review will discuss the current state of the human HIV-1 vaccine trials including the safety consideration of vaccine composition and difficulties in determining and defining protective immunity and epitopes to HIV-1. Vaccines in animal models of lentivirus infection are compared. In particular, the findings from the prototype FIV vaccine and the HIV-1 protein immunizations studies in cats are discussed, as well as the resulting research regarding a potential HIV-1 vaccine design based on evolutionarily conserved T-cell epitopes.
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Authors
J.R. Abbott, M.P. Sanou, J.K. Coleman, J.K. Yamamoto,