| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2463178 | Veterinary Immunology and Immunopathology | 2007 | 9 Pages |
Abstract
IgG1 and IgG2 responses in symptomatic and asymptomatic L. infantum infections differed mainly in subclass production (ELISA values), with higher IgG2 production occurring particularly in symptomatic dogs. Nevertheless, we observed little difference in the idiotype expression of these IgG subclasses, which, in general, recognized the same antigenic fractions. While early L. infantum infection was characterized by recognition of polypeptide fractions of low molecular weight, mainly fractions of 14, 16 and 18Â kDa by IgG1 and 14 and 16Â kDa by IgG2, symptomatology was associated with recognition by both IgG subclasses of a 24Â kDa fraction and other antigens belonging to the AG24 family.
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Authors
Laura Iniesta, Montserrat Gállego, Montserrat Portús,