Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2464787 | The Veterinary Journal | 2011 | 7 Pages |
Abstract
Saliva contains a number of proteins that may be useful as biomarkers of health and disease and can be easily obtained from large numbers of animals in a non-invasive, stress-free way. The objective of this study was to explore the protein composition of porcine saliva from 10 specific pathogen free pigs using first one-dimensional SDS–PAGE and then two-dimensional electrophoresis and mass spectrometry. A reference proteome pattern for porcine saliva was established with the identification of 13 different, mainly saliva-specific, proteins. These reference data will facilitate the investigation of salivary proteins potentially altered in disease and could serve as novel diagnostic biomarkers.
Keywords
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Authors
A.M. Gutiérrez, I. Miller, K. Hummel, K. Nöbauer, S. Martínez-Subiela, E. Razzazi-Fazeli, M. Gemeiner, J.J. Cerón,