Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2467644 | Veterinary Microbiology | 2011 | 6 Pages |
Abstract
Streptococcus suis serotype 2 (S. suis 2) is a pathogen responsible for several diseases in both pigs and humans. To gain more insight into the pathogenesis of this organism, an oligonucleotide (oligo)-based microarray was used to investigate gene expression changes in human monocytic cells (THP-1) in response to exposure to S. suis 2 strain SC19. A total of 328 differentially expressed genes were identified. These differentially expressed genes belonged to a variety of functional categories, including genes involved in apoptosis, immunity, signal transduction, chemokine production and the ubiquitin–proteasome system. Our findings can be of interest for future research.
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Authors
Manli Liu, Chen Tan, Liurong Fang, Shaobo Xiao, Huanchun Chen,