| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2468329 | Veterinary Microbiology | 2009 | 8 Pages |
An appreciation of the complexities of placental structure and function is essential to understanding the pathogenesis of infectious placentitis and abortion. This review aims to illustrate aspects of ovine pregnancy and placentation that will assist both the research worker and the diagnostic pathologist. Morphologically, the ovine placenta is classified as being chorioallantoic, villous, cotyledonary and synepitheliochorial. Apposition of foetal and maternal tissues in early pregnancy eventually leads to the formation of the definitive placenta. Physiological features of placentation that are essential to normal pregnancy and foetal development include modulation of immune responses at the placental interface, increasing placental bloodflow to allow for increasing foetal demand and the secretion of hormones for the recognition and maintenance of pregnancy. Descriptions of the morphology of the near-term placenta in a normal pregnancy and of the foetal membranes that are voided during normal parturition provide the proper context for understanding the morphological changes associated with placentitis and how these changes are likely to affect placental function.
