Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2471865 | Veterinary Parasitology | 2007 | 5 Pages |
Abstract
Metaflumizone, (EZ)-2′-[2-(4-cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-4-(trifluoromethoxy) carbanilohydrazide, was discovered by Nihon Nohyaku in the early 1990s and belongs to the new class of semicarbazone insecticides. It is now being globally co-developed as the animal health product, ProMeris®, in cooperation with Fort Dodge Animal Health and as an agricultural and consumer insecticide in cooperation with BASF. Metaflumizone was developed in a synthesis program initiated from a pyrazoline insecticide lead. In this paper, we describe the development, discovery and structure activity relationships for metaflumizone and related compounds.
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Authors
K. Takagi, H. Hamaguchi, T. Nishimatsu, T. Konno,