Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2471961 | Veterinary Parasitology | 2007 | 6 Pages |
Abstract
Parasitic nematodes of ruminants can be expected to experience temperatures in excess of 40 °C in faeces on pasture and, perhaps, in the host. L3Ostertagia (Teladorsagia) circumcincta survived for at least 90 min at 45 °C in vitro in water, but the larvae were inactivated rapidly by only slightly higher temperatures. The glycolytic enzymes hexokinase and pyruvate kinase were inactivated in a similar temperature range, whereas malate dehydrogenase maintained its activity at temperatures in excess of 50 °C. These data imply that the loss of glycolytic activity might explain the loss of larval motility at temperatures between 45 °C and 50 °C.
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Authors
Lisa R. Walker, David C. Simcock, Jennifer D. Neale, Heather V. Simpson, Simon Brown,