Article ID Journal Published Year Pages File Type
2499371 Experimental and Toxicologic Pathology 2006 11 Pages PDF
Abstract

Breast cancer is the most frequently occurring cancer in women. Treatment options are still an active area of research. Models used for this purpose include induced models in rodents. By the advent of microarrays it has become possible to evaluate models not only for similar morphology or selected markers by polymerase chain reaction (PCR) or immunohistochemistry but also for the expression of thousands of genes at once. This study presents gene expression profiles of the hormone-sensitive 7,12-dimethylbenzanthracene-induced and the metastasising MTLn3-model. The models are discussed for their relevance to breast cancer in humans.

Related Topics
Life Sciences Agricultural and Biological Sciences Animal Science and Zoology
Authors
, , ,