Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2539155 | Fitoterapia | 2010 | 5 Pages |
Two new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2). In vitro, the isolated two new compounds showed significant cytotoxic activities against three human cancer lines, and gave IC50 values in the range OF 2.0-4.2 μΜ.
Graphical abstractTwo new neo-clerodane diterpenoids have been isolated from the whole plant of Scutellaria barbata D. Don, and their structures were established by detailed spectral analyses as scutehenanine H (1) and 6-(2,3-epoxy-2-isopropyl-n-propoxyl)barbatin C (2).Figure optionsDownload full-size imageDownload as PowerPoint slide