Article ID Journal Published Year Pages File Type
2822911 Infection, Genetics and Evolution 2016 10 Pages PDF
Abstract

•CanPV is detected in dogs from Hong Kong and Dubai.•CanPV was clustered with FePV, BatPV 1-3, IaioPV1 and BoPV.•The Ka/Ks ratios of all the coding regions of CanPV were < 0.1.•CanPV, FePV, BatPV 1-3, IaioPV1 and BoPV should constitute a novel genus.

Previously, we reported the discovery of a novel canine picornavirus (CanPV) in the fecal sample of a dog. In this molecular epidemiology study, CanPV was detected in 15 (1.11%) of 1347 canine fecal samples from Hong Kong and one (0.76%) of 131 canine fecal samples from Dubai, with viral loads 1.06 × 103 to 6.64 × 106 copies/ml. Complete genome sequencing and phylogenetic analysis showed that CanPV was clustered with feline picornavirus (FePV), bat picornavirus (BatPV) 1 to 3, Ia io picornavirus 1 (IaioPV1) and bovine picornavirus (BoPV), and this cluster was most closely related to the genera Enterovirus and Sapelovirus. The Ka/Ks ratios of all the coding regions were < 0.1. According to the definition of the Picornavirus Study Group of ICTV, CanPV, FePV, BatPV 1 to 3, IaioPV1 and BoPV should constitute a novel genus in Picornaviridae. BEAST analysis showed that this genus diverged from its most closely related genus, Sapelovirus, about 49 years ago.

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