Article ID Journal Published Year Pages File Type
2822986 Infection, Genetics and Evolution 2016 5 Pages PDF
Abstract

•BrucellaBase currently contains 510 Brucella genome sequences.•It provides BLAST facility exclusively against Brucella spp.•It provides VFDB, CARD, pairwise genome alignment tool for Brucella genomes.•One step MLST typing and phylogeny analysis based on MLST is provided.•MLST typing of 510 genomes are revealed 70 existing sequence types (STs).

Brucella sp. causes a major zoonotic disease, brucellosis. Brucella belongs to the family Brucellaceae under the order Rhizobiales of Alphaproteobacteria. We present BrucellaBase, a web-based platform, providing features of a genome database together with unique analysis tools. We have developed a web version of the multilocus sequence typing (MLST) (Whatmore et al., 2007) and phylogenetic analysis of Brucella spp. BrucellaBase currently contains genome data of 510 Brucella strains along with the user interfaces for BLAST, VFDB, CARD, pairwise genome alignment and MLST typing. Availability of these tools will enable the researchers interested in Brucella to get meaningful information from Brucella genome sequences. BrucellaBase will regularly be updated with new genome sequences, new features along with improvements in genome annotations. BrucellaBase is available online at http://www.dbtbrucellosis.in/brucellabase.html or http://59.99.226.203/brucellabase/homepage.html.

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